For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are ...

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development.

Stopping cancer from coming back is the goal of new research from MUSC Hollings Cancer Center, where scientists are targeting cells that fuel the return of an aggressive pediatric brain tumor.

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

Immunotherapy has transformed cancer care, offering a way to harness the body’s own immune system to fight tumors. But even with these advances, many patients still don’t respond. One major barrier to ...

Kinases that shuttle cholesterol within tumor cells help fuel growth. Blocking these enzymes may starve cancer cells, ...

A new study leverages a modified pyrvinium hybrid to block GLI and WNT pathways, halting pediatric medulloblastoma relapse.

A new study suggests that Resmetirom may do more than treat fatty liver disease — it could also help stop liver cancer from ...

Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...